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A2ML1 Antibody, HRP conjugated

A2ML1 Antibody, HRP conjugated

Quick Overview:

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity). Displays inhibitory activity against chymotrypsin, papain, thermolysin, subtilisin A and, to a lesser extent, elastase but not trypsin. May play an important role during desquamation by inhibiting extracellular proteases.

Product Code: CSB-PA001005LB01HU
Supplier: Cusabio

  • Details

    Recombinant Human Alpha-2-macroglobulin-like protein 1 protein (625-751AA)
  • Additional Information

    Supplier name Cusabio
    Product Type Antibodies
    Size 100ug
    Group (E.g. Primary) Primary
    Concentration 50ug
    Clonality Polyclonal
    Colour Clear solution
    Target/Antigen A2ML1
    Conjugate HRP
    Species Reactivity Human
    Host Species Rabbit
    Isotype IgG
    Applications ELISA
    Storage/Storage buffer Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
    Form Liquid
    Purification >95%, Protein G purified
    Aliases Alpha-2-macroglobulin-like protein 1 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9), A2ML1, CPAMD9
    Publications Publication List
    Datasheet URL View Datasheet
    Categories Antibodies,Primary Antibodies
  • Images