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ALCAM Antibody

ALCAM Antibody

Quick Overview:

Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts (PubMed:7760007, PubMed:15496415, PubMed:15048703, PubMed:16352806, PubMed:23169771, PubMed:24945728). Promotes T-cell activation and proliferation via its interactions with CD6 (PubMed:15048703, PubMed:16352806, PubMed:24945728). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (PubMed:15294938, PubMed:16352806). Mediates homotypic interactions with cells that express ALCAM (PubMed:15496415, PubMed:16352806). Required for normal hematopoietic stem cell engraftment in the bone marrow (PubMed:24740813). Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction (PubMed:23169771). Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions (PubMed:15496415, PubMed:23169771). Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis, required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension, axon growth and axon guidance, axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).

Product Code: CSB-PA614444ESR2HU
Supplier: Cusabio

  • Details

    Recombinant Human CD166 antigen protein (28-180AA)
  • Additional Information

    Supplier name Cusabio
    Product Type Antibodies
    Size 100ul
    Group (E.g. Primary) Primary
    Concentration 100ul
    Clonality Polyclonal
    Colour Clear solution
    Target/Antigen ALCAM
    Conjugate Unconjugated
    Species Reactivity Human, Mouse
    Host Species Rabbit
    Isotype IgG
    Applications ELISA, IHC, WB
    Storage/Storage buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    Form Liquid
    Purification Antigen Affinity Purified
    Aliases CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166), ALCAM, MEMD
    Publications Publication List
    Datasheet URL View Datasheet
    Categories Antibodies,Primary Antibodies
  • Images