ALKBH1 Antibody
Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation (By similarity). Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron.
Details
Recombinant Human Alkylated DNA repair protein alkB homolog 1 protein (110-389AA)
Product Name | ALKBH1 Antibody |
---|---|
Supplier name | Cusabio |
Group (E.g. Primary) | Primary |
Concentration | 100ul |
Clonality | Polyclonal |
Colour | Clear solution |
Product Type | Antibodies |
Conjugate | Unconjugated |
Size | 100ul |
Species Reactivity | Human |
Host Species | Rabbit |
Applications | ELISA, IHC |
Storage/Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Form | Liquid |
Purification | Antigen Affinity Purified |
Isotype | IgG |
Aliases | Nucleic acid dioxygenase ALKBH1 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 1) (Alpha-ketoglutarate-dependent dioxygenase ABH1) (DNA 6mA demethylase) (DNA N6-methyl adenine demethylase) (EC 1.14.11.51) (DNA lyase ABH1) (EC 4.2.99.18) (DNA ox |
Publications | Publication List |
Target/Antigen | ALKBH1 |
Datasheet URL | View Datasheet |