
ACO1 Antibody
Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
Details
Recombinant Human Cytoplasmic aconitate hydratase protein (508-745AA)
Product Name | ACO1 Antibody |
---|---|
Supplier name | Cusabio |
Group (E.g. Primary) | Primary |
Concentration | 50ug |
Clonality | Polyclonal |
Colour | Clear solution |
Product Type | Antibodies |
Conjugate | Unconjugated |
Size | 100ug |
Species Reactivity | Human |
Host Species | Rabbit |
Applications | ELISA, IF, IHC, WB |
Storage/Storage buffer | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Form | Liquid |
Purification | >95%, Protein G purified |
Isotype | IgG |
Aliases | Cytoplasmic aconitate hydratase (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) (Ferritin repressor protein) (Iron regulatory protein 1) (IRP1) (Iron-responsive element-binding protein 1) (IRE-BP 1), ACO1, IREB1 |
Publications | Publication List |
Target/Antigen | ACO1 |
Datasheet URL | View Datasheet |