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ATF4 Antibody

ATF4 Antibody

Quick Overview:

ATF4 is a transcription factor, that accumulates predominantly in osteoblasts, where it regulates terminal osteoblast differentiation and bone formation. As a basic leucine-zipper (bZip) transcription factor, ATF4 can regulate amino acid metabolism, cellular redox state, and anti-stress responses. It also regulates age-related and diet-induced obesity and glucose homeostasis in mammals, and has conserved metabolic functions in flies. Due to its location at chromosome 22q13, a region linked to schizophrenia, ATF4 is considered as a positional candidate gene for schizophrenia. Otherwise, since ATF4 is induced by tumour microenvironmental factors, and regulates processes relevant to cancer progression, it might serve as a potential therapeutic target in cancer. This antibody is a rabbit polyclonal antibody raised against full length human ATF4 antigen.

Product Code: CSB-PA002272KA01HU
Supplier: Cusabio

  • Details

    Recombinant protein of human ATF4
  • Additional Information

    Supplier name Cusabio
    Product Type Antibodies
    Size 100ul
    Group (E.g. Primary) Primary
    Concentration 100ul(100ug)
    Clonality Polyclonal
    Colour Clear solution
    Target/Antigen ATF4
    Conjugate Unconjugated
    Species Reactivity Human, Mouse, Rat
    Host Species Rabbit
    Isotype IgG
    Applications ELISA, IHC, WB
    Storage/Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    Form liquid
    Purification Affinity purification
    Aliases ATF4;CREB-2;CREB2;TAXREB67;TXREB
    Publications Publication List
    Datasheet URL View Datasheet
    Categories Antibodies,Primary Antibodies
  • Images