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ATF4 Antibody

ATF4 Antibody

Quick Overview:

ATF4 is a transcription factor, that accumulates predominantly in osteoblasts, where it regulates terminal osteoblast differentiation and bone formation. As a basic leucine-zipper (bZip) transcription factor, ATF4 can regulate amino acid metabolism, cellular redox state, and anti-stress responses. It also regulates age-related and diet-induced obesity and glucose homeostasis in mammals, and has conserved metabolic functions in flies. Due to its location at chromosome 22q13, a region linked to schizophrenia, ATF4 is considered as a positional candidate gene for schizophrenia. Otherwise, since ATF4 is induced by tumour microenvironmental factors, and regulates processes relevant to cancer progression, it might serve as a potential therapeutic target in cancer. This antibody is a rabbit polyclonal antibody raised against full length human ATF4 antigen.

Product Code: CSB-PA002272KA01HU
Supplier: Cusabio

ATF4 is a transcription factor, that accumulates predominantly in osteoblasts, where it regulates terminal osteoblast differentiation and bone formation. As a basic leucine-zipper (bZip) transcription factor, ATF4 can regulate amino acid metabolism, cellular redox state, and anti-stress responses. It also regulates age-related and diet-induced obesity and glucose homeostasis in mammals, and has conserved metabolic functions in flies. Due to its location at chromosome 22q13, a region linked to schizophrenia, ATF4 is considered as a positional candidate gene for schizophrenia. Otherwise, since ATF4 is induced by tumour microenvironmental factors, and regulates processes relevant to cancer progression, it might serve as a potential therapeutic target in cancer. This antibody is a rabbit polyclonal antibody raised against full length human ATF4 antigen.
Details
Recombinant protein of human ATF4
Additional Information
Product Name ATF4 Antibody
Supplier name Cusabio
Group (E.g. Primary) Primary
Concentration 100ul(100ug)
Clonality Polyclonal
Colour Clear solution
Product Type Antibodies
Conjugate Unconjugated
Size 100ul
Species Reactivity Human, Mouse, Rat
Host Species Rabbit
Applications ELISA, IHC, WB
Storage/Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form liquid
Purification Affinity purification
Isotype IgG
Aliases ATF4;CREB-2;CREB2;TAXREB67;TXREB
Publications Publication List
Target/Antigen ATF4
Datasheet URL View Datasheet

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