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CL097, 500 µg

CL097, 500 µg

Quick Overview:

Product Code: tlrl-c97
Supplier: InvivoGen

  • Details

    TLR7/8 Agonist - Imidazoquinoline compound. CL097 is a highly water-soluble derivative of the imidazoquinoline compound R848 (≥ 20 mg/ml). Similarly to R848, CL097 is a TLR7 and TLR8 ligand [1,2]. It induces the activation of NF-κB at 0.4 µM (0.1 µg/ml) in TLR7-transfected HEK293 cells and at 4 µM (1 µg/ml) in TLR8-transfected HEK293 cells. References: 1 .Salio M. et al., 2007. Modulation of human natural killer T cell ligands on TLR-mediated antigen-presenting cell activation. PNAS 104: 20490 - 20495. 2. Butchi NJ. et al., 2008., Analysis of the Neuroinflammatory Response to TLR7 Stimulation in the Brain: Comparison of Multiple TLR7 and/or TLR8 Agonists. J Immunol 180: 7604-7612.
  • Additional Information

    Supplier name InvivoGen
    Product Type In Vivo Reagents
    Size 500 microg
    Aliases derivative of the imidazoquinoline compound R848
    Publications Publication List
    Datasheet URL View Datasheet
    Categories In Vivo Reagents,PRR ligands
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