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CL401 VacciGrade™, 5 mg

CL401 VacciGrade™, 5 mg

Quick Overview:

Product Code: vac-c401-5
Supplier: InvivoGen

  • Details

    Dual TLR2 & TLR7 agonist CL401 is a chimeric molecule that co-activates the surface receptor TLR2 and the endosomal receptor TLR7. It is composed of 8-hydroxyadenine (TLR7 ligand) conjugated to Pam2C (TLR2 ligand). This chimeric compound displays strong adjuvant activity. In mice, administration of OVA with CL401 leads to a significant increase of anti-OVA IgG titers in sera. The predominant IgG subclass is IgG1, a Th2-associated isotype. The IgG2a subclass, a Th1-associated isotype, is also significantly increased resulting in a decreased IgG1/IgG2a ratio. CL401 VacciGrade™ is suitable for preclinical studies. It is prepared under strict aseptic conditions. It is guaranteed sterile and thoroughly tested for the presence of endotoxins.
  • Additional Information

    Supplier name InvivoGen
    Product Type Reagents
    Size 5 mg,5 mg
    Publications Publication List
    Datasheet URL View Datasheet
    Categories Reagents,Vaccine Adjuvants & Reagents,COVID-19 Products
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