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GAPDH Antibody, FITC conjugated

GAPDH Antibody, FITC conjugated

Quick Overview:

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Product Code: CSB-PA00029C0Rb
Supplier: Cusabio

  • Details

    Recombinant Human Glyceraldehyde-3-phosphate dehydrogenase protein (2-335AA)
  • Additional Information

    Supplier name Cusabio
    Product Type Antibodies
    Size 100ug
    Group (E.g. Primary) Primary
    Concentration 50ug
    Clonality Polyclonal
    Colour Clear solution
    Target/Antigen GAPDH
    Conjugate FITC
    Species Reactivity Human
    Host Species Rabbit
    Isotype IgG
    Applications ELISA
    Storage/Storage buffer Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
    Form Liquid
    Purification >95%, Protein G purified
    Aliases Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-), GAPDH, GAPD
    Publications Publication List
    Datasheet URL View Datasheet
    Categories Antibodies,Primary Antibodies
  • Images