MTM1 Antibody
Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.
Details
Recombinant Human Myotubularin protein (484-603AA)
Product Name | MTM1 Antibody |
---|---|
Supplier name | Cusabio |
Group (E.g. Primary) | Primary |
Concentration | 100ul |
Clonality | Polyclonal |
Colour | Clear solution |
Product Type | Antibodies |
Conjugate | Unconjugated |
Size | 100ul |
Species Reactivity | Human |
Host Species | Rabbit |
Applications | ELISA, IHC |
Storage/Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Form | Liquid |
Purification | Antigen Affinity Purified |
Isotype | IgG |
Aliases | Myotubularin (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64), MTM1, CG2 |
Publications | Publication List |
Target/Antigen | MTM1 |
Datasheet URL | View Datasheet |