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Rabbit anti-Human IgG Fc fragment polyclonal Antibody,Biotin conjugated

Rabbit anti-Human IgG Fc fragment polyclonal Antibody,Biotin conjugated

Quick Overview:

The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody two heavy chains, IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and alpha-2,6 linked sialic acid residues.

Product Code: CSB-PA00540H0Rb
Supplier: Cusabio

  • Details

    The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody two heavy chains, IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and alpha-2,6 linked sialic acid residues.
  • Additional Information

    Supplier name Cusabio
    Product Type Antibodies
    Size 500ug
    Group (E.g. Primary) Secondary
    Concentration 500ug
    Species Reactivity Human
    Host Species Rabbit
    Isotype IgG
    Applications ELISA
    Storage/Storage buffer Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
    Form Liquid
    Publications Publication List
    Datasheet URL View Datasheet
    Categories Antibodies,Secondary Antibodies
  • Images