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THP1-Blue™ ISG Cells

THP1-Blue™ ISG Cells

Quick Overview:

Product Code: thp-isg
Supplier: InvivoGen

  • Details

    Interferon regulatory factor-inducible SEAP Reporter Monocytes. THP1-Blue™ ISG cells were specifically designed for monitoring the interferon signaling pathway in a physiologically relevant cell line. THP1-Blue™ were derived from the human THP-1 monocyte cell line by stable integration of an interferon regulatory factor (IRF)-inducible SEAP reporter construct. As a result, THP1-Blue™ ISG cells allow the monitoring of IRF activation by determining the activity of SEAP. The levels of IRF-induced SEAP in the cell culture supernatant are readily assessed with QUANTI-Blue™, a SEAP detection reagent. THP1-Blue™ ISG cells are highly responsive to PRR agonists that trigger the IFN signaling pathway, such as LPS and transfected double-stranded nucleic acid.
  • Additional Information

    Supplier name InvivoGen
    Product Type Cell & Tissue Culture
    Size 3-7 x 10e6 cells
    Publications Publication List
    Datasheet URL View Datasheet
    Categories Cell & Tissue Culture,Cell Lines,COVID-19 Products
  • Images